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PRP and its Hair Loss Benefits

There have been many important developments in the world of prolotherapy, during the last couple of years. A recent experimental research has apparently warranted a new post on the subject, which is evidently suggesting that PRP injections coupled with stem cells can double up the speedy growth of hair than PRP injections alone. But many of us still are not able to differentiate between the two and hence the current write up has been intended to provide a brief explanation about its effectiveness.


PRP or a platelet rich plasma is an enriched fraction of the blood with suspended platelets, WBC’s and RBC’s. Platelets have been identified to secrete number of good growth factors, that are certainly responsible for stimulating hair growth, when injected into the scalp. However, the research has further suggested that not all PRP can have the same impact on hair growth; in fact, hair loss, can be stopped only if more sophisticated and upgraded technology is been incorporated, wherein concentration of platelet will not be achieved more than 5 or 10 X levels. It has as well been evident that platelet rich plasma when isolated and infused back in the patient’s scalp, its secreted growth factors start degrading immediately, thus stopping further benefits to thinning hair. As a matter of fact, the PRP injections are been offered to be repeated 2-3 times a year to maximize its benefits.

On the contrary, combinational approach of coupling stem cells isolated from patient’s own fat has been found to have better sustainability with effectively improved hair growth and texture over the period of time. These stem cells in fact can act as very good protein matrix or support, to recruit body’s other immunoregulatory cells, internal growth factors and healing proteins; in order to offer continuous nourishments to the weakened hair follicles. Moreover, angiogenic properties of stem cells can actually promote oxygenated blood supply towards the dying follicles, to prevent further hair loss or baldness.

While investigating the frequent causes of hair loss, it has been quite evident that the signaling pathways responsible for circulating chemical messages to and from the hair follicles are halted due to genetic predisposition as well as environmental damage. Thus, untimely hair follicular dwindling may be associated with massive hair thinning, hair loss and/or hair baldness.

Platelet rich plasma and autologous stem cells isolated from patients own fat can make a unique combination to allow signaling of chemical messengers that have been halted; though counteraction at genetic levels. For the enhanced effectiveness and visible treatment outcome, it is being mandatory to infuse stem cells and PRP cocktail, at an optimized concentration and in the crucial areas of hair follicles; where the native stem cells concentration is the highest. This unique approach is found to be the most suitable in activating the follicular growth centers at the different levels of the scalp to give rise to thicker, more robust hair shafts.
Although more extensive research is going on and the better treatment is yet to come, with the current scenario; prolotherapy coupled with the stem cells infusion has been found to be the most valuable adjuvant for hair loss.

The Youthful Me

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